22. Selected Publications

Abercombie, M., Heaysman, J., E., Pegrum, S., M. (1970). The locomotion of fibroblasts in culture. I. Movements of the leading edge. Exp. Cell. Res. 59, 393-398.

 

Akhmanova, A. and Steinmetz, M., O. (2008). Tracking the ends: a dynamic protein network controls the fate of microtubule tips. Nat. Rev. Mol. Cell. Biol. 9, 309-322.  

 

Anderson, K., I., Cross, R. (2000). Contact dynamics during keratocyte motility. Curr. Biol. 10, 253-260.  

 

Anderson, KI., Wang, YL., Small, JV. (1996). Coordination of protrusion and translocation of the keratocyte involves rolling of the cell body. J Cell Biol. 134, 1209-18.

 

Auinger S., Small, J.V. (2008). Correlated light and electron microscopy of the cytoskeleton. Methods Cell Biol. 257-272. (download)

 

Bershadsky, A., Chausovsky, A., Becker, E., Lyubimova, A., Geiger, B. (1996). Involvement of microtubules in the control of adhesion-dependent signal transduction. Curr. Biol. 10, 1279-1289. 

 

Burridge, K. and Chrzanowska-Wodnicka,  M. (1996). Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol. 12, 463-518.

 

Burridge, K., Chrzanowska-Wodnicka M., Zhong C. (1997). Focal Adhesion assembly. Trens Cell Biol. 7, 342-347.

 

Carlier  M., F., Le Clainche, C., Wiesner, S., Pantaloni, D. (2003). Actin-based motility: from molecules to movement. Bioessays 25, 336-345.

 

Chesarone, M., A., Goode, B., L. (2009). Actin nucleation and elongation factors: mechanisms and interplay. Curr. Opin. Cell. Biol. 21, 28-37.

 

Danowski, B., A. (1989). Fibroblast contractility and actin organization are stimulated by microtubule inhibitors. J. Cell. Science. 93, 255-266.

 

Derivery, E. and Gautreau, A. (2010).  Generation of branched actin networks: assembly and regulation of the N-WASP and WAVE molecular machines. Bioessays. 32, 119-131. 

 

Euteneuer U., Schliwa M. (1984). Persistent, directional motility of cells and cytoplasmic fragments in the absence of microtubules. Nature. 5-11;310(5972):58-61.

 

Geiger, B., Spatz, J.,P. and Bershadsky A., D. (2009). Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol. 10, 121-133.

 

Gimona, M., Kaverina, I., Resch, G., P., Vignal, E., Burgstaller, G. (2003). Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells. Mol.Biol. Cell. 14, 2482-2491. 

 

Hall, A. (1998). Rho GTPases and the Actin Cytoskeleton. Science, 279, 509-514.

 

Heasman, S., J. and Ridley,  A., J. (2008). Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat. Rev. Mol. Cell. Biol. 9, 690-701.

 

Hahne, P., Sechi, A., Benesch, S. and Small, J.V. (2001). Scar/WAVE is localised at the tips of protruding lamellipodia in living cells. FEBS Lett. 492, 215-220.

 

Herzog, M., Draeger, A., Ehler, E. and Small, J.V. (1994). Immunofluorence Microscopy of the Cytoskeleton: Double and Triple Immunofluorescence. Cell Biology A Laboratory Handbook, Vol.2, 355-361. 

Kaverina I., Krylyshkina O., Beningo K., Anderson K., Wang YL., Small JV. (2002). Tensile stress stimulates microtubule outgrowth in living cells. J. Cell Sci. 115, 2283-91. (download)

Kaverina, I., Krylyshkina, O., Gimona, M., Beningo, K., Wang, YL., Small, JV. (2000). Enforced polarisation and locomotion of fibroblasts lacking microtubules. Curr Biol. 10, 739-42. (download)

 

Kaverina, I., Krylyshkina, O., Small, JV. (1999). Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J. Cell Biol. 146, 1033-44. (download)

 

Kaverina, I., Krylyshkina, O., Small, JV. (2002). Regulation of substrate adhesion dynamics during cell motility. Int. J. Biochem. Cell Biol. 34, 746-61. (download)

 

Kaverina, I., Rottner, K., Small, JV. (1998). Targeting, capture, and stabilization
of microtubules at early focal adhesions. J. Cell Biol. 142, 181-90. (download)

 

Koestler, SA., Auinger, S., Vinzenz, M., Rottner K., Small, JV. (2008). Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front. Nat Cell Biol. 10, 306-313. (download)

 

Krylyshkina, O., Anderson, KI., Kaverina, I., Upmann, I., Manstein, DJ., Small, JV., Toomre, DK. (2003). Nanometer targeting of microtubules to focal adhesions. J. Cell Biol. 161, 853-9. (download)

 

Krylyshkina, O., Kaverina, I., Kranewitter, W., Steffen, W., Alonso, MC., Cross, RA., Small, JV. (2002). Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J. Cell Biol. 156, 349-59. (download)

 

Lai, F.P.L., Szczodrak, M., Block, J., Mannherz, H.G., Small, J.V., Stradal, T.E.B., Dunn, G.A. and Rottner G.A.K. (2008). Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J. 27, 982-992. (download)

Nakagawa, H., Miki, H. Nozumi, M. Takenawa, T. Miyamoto, S. Wehland, J. and Small, J.V. (2003). IRSp53 is co-localised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena. J Cell Sci. 116, 2577-83. (download)

 

Nemethova, M., Auinger, S., Small, J.V. (2008). Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella. J Cell Biol. 180, 1233-1244. (download)

 

Pantaloni, D., Le Clainche C., Carlier, M.F. (2001). Mechanism of actin-based motility. Science. 292, 1502-1506.

 

Pollard, T., D. and Borisy, G., G. (2003). Cellular motility driven by assembly and disassembly of actin filaments. Cell. 112, 453-465.

 

Resch, GP., Goldie, KN., Hoenger, A., Small, JV. (2002). Pure F-actin networks are distorted and branched by steps in the critical-point drying method. J. Struct Biol. 137, 305-12. (download)

Resch, GP., Goldie, KN., Krebs, A., Hoenger, A., Small, JV. (2002). Visualisation of the actin cytoskeleton by cryo-electron microscopy. J. Cell Sci. 115, 1877-82. (download)

 
Rid R., Schiefermeier N., Grigoriev I., Small JV., Kaverina I. (2005). The last but not the least: the origin and significance of trailing adhesions in fibroblastic cells. Cell Motil Cytoskeleton. 61, 161-71. (download)

 

Riveline, D., Zamir E., Balaban, N., Q., Schwarz, S., U., Ishizaki, T., Narumiya, S., Kam, Z., Geiger, B., Bershadsky, A., D. (2001). Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J. Cell. Biol. 11, 1175-1186. 

 

Rottner, K., Behrendt, B., Small, JV, Wehland, J. (1999). VASP dynamics during lamellipodia protrusion. Nat. Cell. Biol. 1, 321-322. (download)

 

Rottner, K., Hall, A., Small, JV. (1999). Interplay between Rac and Rho in the control of substrate contact dynamics. Curr. Biol. 9, 640-8. (download)

Rottner, K., Krause, M., Gimona, M., Small, JV., Wehland, J. (2001). Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions. Mol. Biol Cell. 12, 3103-13. (download)

 

Schuyler, S.C., Pellman, D. (2001). Microtubule "plus-end-tracking proteins": The end is just the beginning. Cell. 18, 421-424.

 

Small, JV. (1981). Organization of actin in the leading edge of cultured cells: influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks. J. Cell Biol. 91, 695-705. (download)

 

Small, JV., The actin cytoskeleton. (1988). Electron Microsc Rev. 1, 155-74. (download)

 

Small, JV, Anderson, K, Rottner, K. (1996). Actin and the coordination of protrusion, attachment and retraction in cell crawling. Biosci Rep. 16, 351-68. (download)

 

Small, JV., Celis, JE. (1978a). Filament arrangements in negatively stained cultured cells: the organization of actin. Cytobiologie 16, 308-25. (download)

 

Small, JV., Celis, JE. (1978b). Direct Visualization of the 10nm (100-A)-Filament Network in Whole and Enucleated Cultured Cells. J. Cell. Sci. 31, 393-409. (download)

 

Small, JV., Celis, JE., Isenberg, G. (1980). Aspects of Cell Architecture and Locomotion. Transfer of Cell Constituents into Eukaryotic Cells (Celis, JE., Graessmann, A., Loyter, A.). (download)

 

Small, JV., Geiger, B., Kaverina, I., Bershadsky, A. (2002). How do microtubules guide migrating cells? Nat. Rev. Mol. Cell Biol. 3, 957-64. (download)

 

Small JV., Herzog, M., Anderson, K. (1995). Actin filament organization in the fish keratocyte lamellipodium. J. Cell Biol. 129, 1275-86. (download)

 

Small, JV., Kaverina, I. (2003). Microtubules meet substrate adhesions to arrange cell polarity. Curr. Opin. Cell Biol. 15, 40-7. (download)

Small, JV., Resch, GP. (2005). The comings and goings of actin: coupling protrusion and retraction in cell motility. Curr. Opin. Cell. Biol. 17, 517-523. (download)

Small, JV., Rinnerthaler, G, Hinssen, H. (1982). Organization of actin meshworks in cultured cells: the leading edge. Cold Spring Harb Symp Quant Biol. 46, 599-611. (download) 

Small, JV., Rottner, K., Hahne, P., Anderson, KI. (1999). Visualising the actin cytoskeleton. Microsc. Res. Tech. 47, 3-17. (download)

Small, J.V., Rottner, K.R. (2010). Elementary Cellular Processes Driven by Actin Assembly: Lamellipodia and Filopodia. In “Actin-based Motility” Ed by M.F. Carlier, pp 3-33, Springer Science. (download)

Small, JV., Stradal, T., Vignal, E. and Rottner, K. (2002). The lamellipodium: where motility begins. Trends Cell Biol., 12, 112-120. (download)

Steffen, A., Faix, J., Resch, GP., Linkner, J., Wehland, J., Small, JV., Rottner, K., Stradal, TE. (2006). Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes.  Mol Biol Cell. 17, 2581-91. (downlaod)

Stradal, T., Courtney, KD., Rottner, K., Hahne, P., Small, JV. and Pendergast, AM. (2001). The Abl-interactor (Abi) proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia. Curr. Biol. 11, 891-895. (download)

 

Stradal,  T., E., Rottner, K., Disanza, A., Confalonieri, S.,  Innocenti, M., Scita, G. (2004). Regulation of actin dynamics by WASP and WAVE family proteins. Trends Cell. Biol. 14, 303-311.

 

Takenawa, T., Suetsugu, S. (2007). The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. Nat. Rev. Mol. Cell. Biol. 8, 37-48.

 

Toomre, D. and Manstein, D., J. (2001). Lighting up the cell surface with evanescent wave microscopy. Trends Cell. Biol. 11, 298-303.

 

Urban, E., Jacob, S., Nemethova, M., Resch, G., P., Small, J., V. (April, 2010). Actin network organization in lamellipodia revealed by electron tomography. Nat. Cell. Biol. online.

 

Vasiliev, J., M. (1985). Spreading of non-transformed and transformed cells. Biochim Biophys Acta. 780, 21-65.

 

Verkhovsky, A., B., Svitkina, T., M., Borisy, G., G. (1998). Self-polarization and directional motility of cytoplasm. Curr. Biol. 9, 11-20.

Vignal, E., Resch, GP. (2003). Shedding light and electrons on the lamellipodium: imaging the motor of crawling cells. Biotechniques. 34, 780-4, 786, 788-9. (download)